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Dieldrin and Breast Cancer Risk
Bibliography

This bibliography is provided as a service to our readers. It is compiled from the entries in the BCERF Environmental Risk Factors Bibliographic Database.

This bibliography is arranged topically. The topics include:

Toxicology Reviews on Dieldrin

Ahlborg, U. G., Lipworth, L., Titus-Ernstoff, L., Hsieh, C.-C., Hanberg, A., Baron, J., Trichopoulos, D., and Adami, H.-O. (1995). Organochlorine compounds in relation to breast cancer, endometrial cancer, and endometriosis: An assessment of the biological and epidemiological evidence. Critical Reviews in Toxicology 25, 463-531.

ATSDR. (1997). Agency for Toxic Substances and Disease Registry ToxFAQs™ MENU (http://atsdr1.atsdr.cdc.gov:8080/toxfaqta.html: ATSDR).

IARC. (1987). Overall evaluations of carcinogenicity: an updating of IARC Monographs volumes 1 to 42; Dieldrin (Group 3). In IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans (Lyon, France: International Agency for Research on Cancer, World Health Organization), pp. 196-197.

Jorgenson, J.L. (2001) Aldrin and dieldrin: A review of research on their production, environmental deposition and fate, bioaccumulation, toxicology, and epidemiology in the United States. Environmental Health Perspectives 109 (supp1):113-139.

Smith, A. G. (1991). Chlorinated Hydrocarbon Insecticides, Section 15.5. Cyclodiene and Related Compounds. In Handbook of Pesticide Toxicology, W. J. Hayes, Jr. and E. R. Laws, Jr., eds. (San Diego, California: Academic Press, Inc.), pp. 816-850.

Dieldrin and the Risk of Breast Cancer

Aschengrau, A., Coogan, P. F., Quinn, M. M., and Cashins, L. J. (1998). Occupational exposure to estrogenic chemicals and the occurrence of breast cancer: An exploratory analysis. American Journal of Industrial Medicine 34, 6-14.

Djordjevic, M. V., Hoffmann, D., Fan, J., Prokopczyk, B., Citron, M. L., and Stellman, S. D. (1994). Assessment of chlorinated pesticides and polychlorinated biphenyls in adipose breast tissue using a supercritical fluid extraction method. Carcinogenesis 15, 2581-2585.

Dorgan, J. F., Brock, J. W., Rothman, N., Needham, L. L., Miller, R., Stephenson, H. E., Jr., Schussler, N., and Taylor, P. R. (1999). Serum organochlorine pesticides and PCBs and breast cancer risk: results from a prospective analysis (USA). Cancer Causes and Control 10, 1-11.

Høyer, A., Jørgensen, T., Brock, J., and Grandjean, P. (2000). Organochlorine exposure and breast cancer survival. Journal of Clinical Epidemiology 53, 323-330.

Høyer, A. P., Grandiean, P., Jørgensen, T., Brock, J. W., and Hartvig, H. B. (1998). Organochloride exposure and risk of breast cancer. Lancet 352, 1816-1820.

Ward, E. M., Schulte, P., Grajewski, B., Andersen, A., Patterson, D. G., Jr., Turner, W., Jellum, E., Deddens, J. A., Friedland, J., Roeleveld, N., Waters, M., Butler, M. A., DiPietro, E., and Needham, L. L. (2000). Serum organochlorine levels and breast cancer: A nested case-control study of Norwegian women. Cancer Epidemiology, Biomarkers & Prevention 9, 1357-1367.

Wassermann, M., Nogueira, D. P., Tomatis, L., Mirra, A. P., Shibata, H., Arie, G., Cucos, S., and Wassermann, D. (1976). Organochlorine compounds in neoplastic and adjacent apparently normal breast tissue. Bulletin of Environmental Contamination and Toxicology 15, 478-484.

Dieldin and the Risk of Other Cancers (non-breast cancers)

Brown, D. P. (1992). Mortality of workers employed at organochlorine pesticide manufacturing plants - An update. Scandinavian Journal of Work, Environment and Health 18, 155-161.

CSA (1988). Cancer risk of pesticides in agricultural workers. Journal of American Medical Association 260, 959-966.

Metcalfe, C. D., Cairns, V. W., and Fitzsimons, J. D. (1988). Experimental induction of liver tumours in rainbow trout (Salmo gairdneri) by contaminated sediment from Hamilton Harbour, Ontario. Canadian Journal of Fisheries and Aquatic Sciences 45, 2161-2167.

Sturgeon, S. R., Brock, J. W., Potischman, N., Needham, L. L., Rothman, N., Brinton, L. A., and Hoover, R. N. (1998). Serum concentrations of organochlorine compounds and endometrial cancer risk (United States). Cancer Causes and Control 9, 417-424.

Evidence of Estrogenicity of Dieldrin

Arnold, S. F., Vonier, P. M., Collins, B. M., Klotz, D. M., Guillette Jr., L. J., and McLachlan, J. A. (1997). In vitro synergistic interaction of alligator and human estrogen receptors with combinations of environmental chemicals. Environmental Health Perspectives 105, 615-618.

Bolger, R., Wiese, T. E., Ervin, K., Nestich, S., and Checovich, W. (1998). Rapid screening of environmental chemicals for estrogen receptor binding capacity. Environmental Health Perspectives 106, 551-557.

Danzo, B. J. (1997). Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins. Environmental Health Perspectives 105, 294-301.

Guillette, L. J., Jr., Arnold, S. F., and McLachlan, J. A. (1996). Ecoestrogens and embryos-Is there a scientific basis for concern? Animal Reproduction Science 42, 13-24.

Legler, J., van den Brink, C. E., Brouwer, A., Murk, A. J., van der Saag, P. T., Vethaak, A. D., and van der Burg, B. (1999). Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line. Toxicological Science 48, 55-66.

Ramamoorthy, K., Wang, F., Chen, I.-C., Norris, J. D., McDonnell, D. P., Leonard, L. S., Gaido, K. W., Bocchinfuso, W. P., Korach, K. S., and Safe, S. (1997). Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast- based estrogen receptor assays: no apparent synergism. Endocrinology 138, 1520-1527.

Soto, A. M., Chung, K. L., and Sonnenschein, C. (1994). The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells. Environmental Health Perspectives 102, 380-383.

Soto, A. M., Sonnenschein, C., Chung, K. L., Fernandez, M. F., Olea, N., and Serrano, F. O. (1995). The E-Screen Assay as a tool to identify estrogens: an update on estrogenic environmental pollutants. Environmental Health Perspectives 103, 113-122.

Vonier, P. M., Crain, D. A., McLachlan, J. A., Guillette, L. J., Jr., and Arnold, S. F. (1996). Interaction of environmental chemicals with the estrogen and progesterone receptors from the oviduct of the American alligator. Environmental Health Perspectives 104, 1318-1322.

Wade, M. G., Desauliners, D., Leingartner, K., and Foster, W. G. (1997). Interactions between endosulfan and dieldrin on estrogen-mediated processes in vitro and in vivo. Reproductive Toxicology 11, 791-798.

Levels of Dieldrin in Breast Milk

Donma, M. M., and Donma, O. (1996). Evaluation of various aspects of paediatric malignancies in Turkey and Turkey's status in health statistics. Medical Hypotheses 46, 281-285.

Jensen, A. A., and Slorach, S. A. (1991). Chemical Contaminants in Human Milk (Boca Raton: CRC Press).

Luke, M. A., Masumoto, H. T., Cairns, T., and Hundley, H. K. (1988). Levels and incidences of pesticide residues in various foods and animal feeds analyzed by the Luke multiresidue methodology for fiscal years 1982-1986. Journal Association of Official Analytical Chemists 71, 415-433.

Newsome, W. H., and Ryan, J. J. (1999). Toxaphene and other chlorinated compounds in human milk from northern and southern Canada: a comparison. Chemosphere 39, 519-526.

Rogan, W. J., Blanton, P. J., Portier, C. J., and Stallard, E. (1991). Should the presence of carcinogens in breast milk discourage breast feeding? Regulatory Toxicology and Pharmacology 13, 228-240.

Levels of Dieldrin in Food

Ahmad, N., Bugueno, G., Guo, L., and Marolt, R. (1999). Determination of organochlorine and organophosphate pesticide residues in fruits, vegetables and sediments. Journal of Environmental Science and Health 34, 829-848.

de la Riva, C., and Andon, A. (1991). Organochlorine pesticides in cow's milk from agricultural region in northwestern Spain. Bulletin of Environmental Contamination and Toxicology 46, 527- 533.

Hargrave, B. T., Harding, G. C., Vass, W. P., Erickson, P. E., Fowler, B. R., and Scott, V. (1992). Organochlorine pesticides and polychlorinated biphenyls in the Arctic ocean food web. Archives of Environmental Contamination and Toxicology 22, 41-54.

Hellou, J., Parsons, D., and Mercer, G. (1997). Organochlorine contaminants in the northern shrimp, Pandalus borealis, collected from the Northwest Atlantic. Marine Environmental Research 44, 99-113.

Jensen, A. A., and Slorach, S. A. (1991). Chemical Contaminants in Human Milk (Boca Raton: CRC Press).

Lovell, R. A., McChesney, D. G., and Price, W. D. (1996). Organohalogen and organophosphorus pesticides in mixed feed rations: Findings from FDA's domestic surveillance during fiscal years 1989-1994. Journal of AOAC International 79, 544-548.

Travis, C. C., and Arms, A. D. (1988). Bioconcentration of organics in beef, milk, and vegetation. Environmental Science and Technology 22, 271-274.

Trotter, W. J., and Dickerson, R. (1993). Pesticide residues in composited milk collected through the U. S. pasteurized milk network. Journal of AOAC International 76, 1220-1225.

Yess, N. J., Houston, M. G., and Gunderson, E. L. (1991). Food and Drug Administration pesticide residue monitoring of foods: 1978-1982. Journal of the Association of Official Analytical Chemists 74, 265-272.

Exposure to Dieldrin in Environment and the Home

Ahlborg, U. G., Lipworth, L., Titus-Ernstoff, L., Hsieh, C.-C., Hanberg, A., Baron, J., Trichopoulos, D., and Adami, H.-O. (1995). Organochlorine compounds in relation to breast cancer, endometrial cancer, and endometriosis: An assessment of the biological and epidemiological evidence. Critical Reviews in Toxicology 25, 463-531.

Alexander, M. (1997). Contaminated sites may be less risky than thought. In Centerpoint.

Alexander, M. (1997). Sequestration and bioavailability of organic compounds in soil. In Environmentally Acceptable Endpoints in Soil, D. G. Linz and D. V. Nakles, eds. (Annapolis, MD: American Academy of Environmental Engineers), pp. 43-136.

Barbash, J. E., and Resek, E. A. (2000). Chapter 4, Processes that Govern Pesticide Concentration in Ground Water. In Pesticides in Ground Water; Distribution, Trends and Governing Factors, R. J. Gilliom, ed. (Boca Raton: Lewis Publishers), pp. 179-232.

Camann, D. E. (1994). Investigating the effects of pesticide exposure in the home. Technology Today, 2-7.

Dewailly, E., Ayotte, P., Bruneau, S., Gingras, S., Belles-Isles, M., and Roy, R. (2000). Susceptibility to infections and immune status in Inuit infants exposed to organochlorines. Environmental Health Perspectives 108, 205-211.

Eckhardt, D. A. V., and Stackelberg, P. E. (1995). Relation of ground-water quality to land use on Long Island, New York. Ground Water 33, 1019-1033.

Fisher, B. (1999). Most unwanted persistent organic pollutants: aldrin, chlordane, DDT, dieldrin, dioxins and furans, endrin, heptachlor, HCB, mirex, PCBS, and toxaphene. Environmental Health Perspectives 107, A18-A23.

Kolpin, D. W., Barbash, J. E., and Gillion, R. J. (1998). Occurrence of pesticides in shallow groundwater of the United States: Initial results from the National Water-Quality Assessment Program. Environmental Science and Technology 32, 558-566.

Jørgenson, J.L. (2001) Aldrin and dieldrin: A review of research on their production, environmental deposition and fate, bioaccumulation, toxicology, and epidemiology in the United States. Environmental Health Perspectives 109 (supp1):113-139.

Martijn, A., Bakker, H., and Schreuder, R. H. (1993). Soil persistence of DDT, dieldrin, and lindane over a long period. Bulletin of Environmental Contamination and Toxicology 51, 178- 184.

Phillips, P. J., Eckhardt, D. A., Terraccinano, S. A., and Rosenman, L. (1999). Pesticides and their metabolites in wells of Suffolk County, New York, 1998. U.S.G.S. WRIR 99-4095 (Denver, CO: U.S. Geological Survey).

Salama, A. K., Bakry, N. M., and Abou-Donia, M. B. (1993). A review article on placental transfer of pesticides. Journal of Occupational Medicine and Toxicology 2, 383-397.

Schmidt, C. W. (1999). Spheres of influence. Environmental Health Perspectives 107, A24-A25.

Starr, H. G., Jr., Aldrich, F. D., McDougall, W. D., III, and Mounce, L. M. (1974). Contribution of household dust to the human exposure to pesticides. Pesticides Monitoring Journal 8, 209-212.

USGS. (2000). Pesticides in stream sediment and aquatic biota, USGS fact Sheet 092-00: U.S. Geological Survey), pp. 1-4.

Levels of Dieldrin in Human Tissue

Cantoni, C., and Comi, G. (1997). Changes in the concentrations of pesticide residues in foods and in human tissues between 1960 and 1996. Outlook on Agriculture 26, 47-52.

Kutz, F. W., Wood, P. H., and Bottimore, D. P. (1991). Organochlorine pesticides and polychlorinated biphenyls in human adipose tissue. Reviews of Environmental Contamination and Toxicology 120, 1-82.

Kutz, F. W., Yobs, A. R., and Strassman, S. C. (1977). Racial stratification of organochlorine insecticide residues in human adipose tissue. Journal of Occupational Medicine 19, 619-622.

Murphy, R. S., Kutz, F. W., and Strassman, S. C. (1983). Selected pesticide residues or metabolites in blood and urine specimens from a general population survey. Environmental Health Perspectives 48, 81-86.

Sim, M., Forbes, A., McNeil, J., and Roberts, G. (1998). Termite control and other determinants of high body burdens of cyclodiene insecticides. Archives of Environmental Health 53, 114-121.

Teschke, K., Kelly, S. J., Wiens, M., Hertzman, C., Dimich-Ward, H., Ward, J. E. H., and van Oostdam, J. C. (1993). Concentrations of organochlorine pesticides in the adipose tissue of British Columbia residents. Canadian Journal of Public Health 84, 192-196.

Thomas, K. B., and Colborn, T. (1992). Organochlorine endocrine disruptors in human tissue. In Chemically-Induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection, T. Colborn and C. Clement, eds. (Racine, WI: Princeton Scientific Publishing Co. Inc.), pp. 365-394.

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Prepared by Suzanne Snedeker, Ph.D. BCERF Research Project Leader and
Kola Ijola, Research Assistant

We will make every effort to update this bibliography. If you have comments on this bibliography, or have a suggestion of a reference you would like us to review for inclusion in the bibliography, please send this information via email to: breastcancer@cornell.edu

Last Update 05.06.03